PEP is given to the infant within 4 hours of birth and may be given orally, although it can also be given via a nasogastric tube or intravenously. In most cases, if the baby is categorised as ‘very low risk’ or ‘low risk’ of HIV transmission, PEP will be administered for 2 weeks, twice daily in a two-drug combination. If the risk of transmission is considered high, PEP may be given for 4-6 weeks and is usually in the form of triple combination therapy (6). 

British HIV Association (BHIVA) guidelines for the management of HIV in pregnancy and postpartum 2018 (6).