Ageing with HIV infection

Major reductions in HIV-associated mortality have increased the median life expectancy of adults with HIV infection. However, immunodeficiency and illnesses involving inflammatory processes e.g. cardiovascular, bone, renal and liver disease, cancers and neurocognitive decline are clustering in older people with HIV infection leading to a “geriatric syndrome” not usually seen in individuals without HIV infection …

The Geriatric Syndromes: Frailty, Multimorbidity and Polypharmacy Read More »

“Ageing with HIV” is associated with a higher frequency of (1) multimorbidity, possibly attributable to previous toxic exposure to ART and lifestyle factors; (2) polypharmacy due to ART and other medications for co-morbidities, compared with “typical” ageing.[10] It is clear a structural and cultural change in standard patient assessment and transition in care, needs to …

Comprehensive geriatric assessment and a change in approach to the care of ageing people with HIV infection Read More »

End-of-life planning is important and relevant for all people with HIV infection. Planning and advance care directives have been shown to improve care for patients and psychosocial outcomes in surviving relatives. [139, 140] HIV infection can complicate care at the end of life but past research in other contexts has indicated that people with HIV …

End-of-life care Read More »

  Lagathu C, Cossarizza A, Bereziat V, Nasi M, Capeau J, Pinti M. Basic science and pathogenesis of ageing with HIV: potential mechanisms and biomarkers. AIDS 2017; 31 Suppl 2: S105-S19. Kirby Institute. HIV, viral hepatitis and sexually transmissible infections in Australia: Annual Surveillance Report 2018. Available at: https://kirby.unsw.edu.au/sites/default/files/kirby/report/KI_Annual-Surveillance-Report-2018.pdf. Accessed December 14th. Guaraldi G, Palella …

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