Iryna Zablotska1, John McAllister2 The University of Sydney, Sydney, NSW St. Vincent’s Hospital, Sydney, Darlinghurst, Sydney, NSW Last reviewed: November 2019 Background The HIV epidemic in Australia Australia has a concentrated human immunodeficiency virus (HIV) epidemic. In 2018, sexual contact between men accounted for approximately 70% of new HIV diagnoses; heterosexual exposure contributed 23%, and …
MSM represent the predominant part of the Australian population at most risk of HIV infection. The most effective way to prevent the sexual transmission of HIV and other STIs is to prevent exposure. Condom use and other behavioural methods of risk reduction, such as HIV serosorting, strategic positioning, negotiated safe practices with sexual partners and …
Terminology Treatment as prevention (TasP) refers to the use of antiretroviral drugs to decrease the risk of HIV transmission. When taken consistently, antiretroviral drugs can reduce the HIV viral load in an HIV-infected individual’s blood, semen, vaginal fluid and rectal fluid to a level at which blood tests cannot detect the virus [17]. Such viral …
Terminology Post-exposure prophylaxis (PEP) was one of the first strategies to employ antiretroviral drugs for the prevention of HIV infection. It involves a 28-day course of antiretroviral drugs initiated within 72 hours of a potential high-risk exposure to HIV. [37] The concept of PEP and evidence of its efficacy Animal models showed that within 3-5 …
Terminology WHO defines pre-exposure prophylaxis (PrEP) as the use of oral tenofovir disoproxil fumarate (TDF) or co-formulated TDF/emtricitabine (TDF/FTC) or co-formulated TDF/lamivudine (TDF/3TC) by HIV-negative people to prevent HIV acquisition (FTC and 3TC are considered interchangeable). In 2019, the US Food and Drug Administration approved emtricitabine + tenofovir alafenamide (FTC/TAF or F/TAF, Descovy®) as another …
Biomedical strategies based on the use of antiretroviral drugs are currently front and centre stage of HIV prevention. General practitioners and nurses have a key role in service provision, education, support and innovative research as TasP, PEP and PrEP assume a more prominent role in HIV prevention.
Remis RS, Alary M, Liu J, Kaul R, Palmer RWH. HIV transmission among men who have sex with men due to condom failure. PLOS ONE 2014; 9: e107540. Australian Clinical Supervision Association (ACSA). Clinical Supervision: A Working Definition. ACSA Definitions Report. Forest Lake, Qld, 2014. URL (last accessed on 30 October 2019): http://clinicalsupervision.org.au/wp-content/uploads/2014/10/ACSA-Definitions-Report-Final-2014.pdf. Cardo DM, …
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