Adult Antiretroviral Guidelines

US DHHS Guidelines with Australian Commentary

General Terms

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Adult Guidelines > > Appendix A: Key to Acronyms > General Terms
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General Terms

DHHS Last Updated: March 2023

Acronym/Abbreviation Definition
17-BMP beclomethasone 17-monopropionate
ACA Affordable Care Act
ADAP AIDS Drug Assistance Program
Ag/Ab antigen/antibody
Al aluminum
ALT alanine aminotransferase
AMP average manufacturer price
ART antiretroviral therapy
ARTAS Anti-Retroviral Treatment and Access to Services
ARV antiretroviral
ASP average sales price
AST aspartate aminotransferase
AUC area under the curve
AUD alcohol use disorder
AUDIT-C Alcohol Use Disorders Identification Test-Consumption
AV atrioventricular
AWP average wholesale price
AYA adolescents and young adults
BMD bone mineral density
BUN blood urea nitrogen
Ca calcium
CaCO3 calcium carbonate
CBC complete blood count
CCB calcium channel blockers
CD4 CD4 T lymphocyte
CDC Centers for Disease Control and Prevention
CHF congestive heart failure
CI confidence interval, capsid inhibitor
CKD chronic kidney disease
Cl chloride
Cmax maximum plasma concentration
Cmin minimum plasma concentration
CMV cytomegalovirus
CNS central nervous system
COC combined oral contraceptive
CPI-U consumer price index-urban
CPK creatine phosphokinase
Cr creatinine
CrCl creatinine clearance
CSF cerebrospinal fluid
CV cardiovascular
CVD cardiovascular disease
CYP cytochrome P450
D/M dual/mixed
DAA direct-acting antiviral
DHA dihydroartemisinin
DILI drug-induced liver injury
DM diabetes mellitus
DMPA depot medroxyprogesterone acetate
DOT directly observed therapy
EBV Epstein-Barr virus
ECG electrocardiogram
eGFR estimated glomerular filtration rate
ESRD end stage renal disease
FCP federal price ceiling
FDA U.S. Food and Drug Administration
FDC fixed-dose combination
Fe iron
FUL federal upper limit
GAHT gender-affirming hormone therapy
GHB gamma-hydroxybutyrate
GI gastrointestinal
gp glycoprotein
GS Gilead Sciences
H2 histamine 2
H2RA H2 receptor antagonist
HAD HIV-associated dementia
HAND HIV-associated neurocognitive disorder
HAV hepatitis A virus
HbA1C hemoglobin A1c
HBcAb hepatitis B core antibody
HBeAg hepatitis B e antigen
HBsAb hepatitis B surface antibody
HBsAg hepatitis B surface antigen
HBV hepatitis B virus
HCC hepatocellular carcinoma
HCO3 bicarbonate
HCV hepatitis C virus
HD hemodialysis
HDL high-density lipoprotein
HHS U.S. Department of Health and Human Services
HIV human immunodeficiency virus
HIV RNA HIV viral load
HIV-1 human immunodeficiency virus type 1
HIV-2 human immunodeficiency virus type 2
HIVMA/IDSA HIV Medicine Association of the Infectious Diseases Society of America
HLA human leukocyte antigen
HMG-CoA hydroxy-methylglutaryl-coenzyme A
HR hazard ratio
HRSA Health Resources and Services Administration
HRT hormone replacement therapy
hs-CRP high-sensitivity C-reactive protein
HSR hypersensitivity reaction
HTLV-1 human T-lymphotropic virus-1 type I
IAS–USA International AIDS Society–USA
IC50 inhibitory concentration
IL interleukin
IM intramuscular
IN integrase
INR international normalized ratio
INSTI integrase strand transfer inhibitor
IPT isoniazid preventive therapy
IRIS immune reconstitution inflammatory syndrome
ISR injection site reactions
IUD intrauterine device
IV intravenous
K potassium
LA-ART long-acting ART
LAI long-acting injectable
LDL low-density lipoprotein
LGBTQ lesbian, gay, bisexual, transgender, or queer
LLOD lower limits of detection
LTBI latent tuberculosis infection
MAC Mycobacterium avium complex
MAT medication-assisted treatment
MATE multidrug and toxin extrusion transporter
MDR multidrug resistant
MDR-TB multidrug-resistant tuberculosis
MDMA methylenedioxymethamphetamine
MDRP Medicaid Drug Rebate Program
MET motivational enhancement therapy
Mg magnesium
MHC major histocompatibility complex
MI motivational interviewing
MI myocardial infarction
MPA medroxyprogesterone acetate
MRI magnetic resonance imaging
MSM men who have sex with men
MTR multi-tablet regimen
N/A not applicable
Na sodium
NA-ACCORD North American AIDS Cohort Collaboration on Research and Design
NIH National Institutes of Health
NNRTI non-nucleoside reverse transcriptase inhibitor
NRTI nucleoside/nucleotide reverse transcriptase inhibitor
NTD neural tube defect
OARAC Office of AIDS Research Advisory Council
OAT opioid agonist therapy
OATP organic anion-transporting polypeptide
OBR optimized background regimen
OCT2 organic cation transporter 2
OH-itraconazole active metabolite of itraconazole
OI opportunistic infection
ONDCP Office of National Drug Control Policy
OR odds ratio
OTP opioid treatment program
OUD opioid use disorder
P phosphorus
P-gp p-glycoprotein
PAH pulmonary arterial hypertension
PBM pharmacy benefit manager
PCP Pneumocystis jirovecii pneumonia
PCR polymerase chain reaction
PDE5 phosphodiesterase type 5
PHQ-2 Patient Health Questionnaire-2
PEP post-exposure prophylaxis
PI protease inhibitor
PI/c cobicistat-boosted protease inhibitor
PI/r ritonavir-boosted protease inhibitor
PK pharmacokinetic
PO orally
PPI proton pump inhibitor
PR protease
PrEP pre-exposure prophylaxis
PTH parathyroid hormone
QTc QT corrected for heart rate
REPC Retention through Enhanced Personal Contact
RNA ribonucleic acid
RT reverse transcriptase
RWHAP Ryan White HIV/AIDS Program
SAMHSA Substance Abuse and Mental Health Services Administration
SCr serum creatinine
SJS Stevens Johnson Syndrome
SMAC state maximum allowable cost
SMR sexual maturity rating
SPT skin patch test
SQ subcutaneous
SSRI selective serotonin reuptake inhibitor
STI sexually transmitted infection
STR single-tablet regimen
SUD substance use disorder
TasP treatment as prevention
TB tuberculosis
TC total cholesterol
TCA tricyclic antidepressant
TDM therapeutic drug monitoring
TDR transmitted drug resistance
TG triglyceride
The Panel The Panel on Antiretroviral Guidelines for Adults and Adolescents
THRIVE Targeting HIV Retention and Improved Viral load through Engagement
U = U Undetectable = Untransmittable
UGT uridine diphosphate glucuronosyltransferase
UGT1 uridine diphosphate glucuronyltransferase 1 family
UGT1A1 uridine diphosphate glucuronosyltransferase 1A1
ULN upper limit of normal
USTS U.S. Transgender Survey
UW University of Washington
VL viral load
VPA valproic acid
WAC wholesale acquisition cost
WBC white blood cell
WHO World Health Organization
WPATH World Professional Association for Transgender Health
XDR extensively drug resistant
XR extended release
Zn zinc
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