Among patients with PRP in the setting of newly diagnosed HIV infection, commencement of ART alone has been reported to induce cutaneous remission. (133, 134) Due to its rarity, management guidelines are based on retrospective studies and case series, and may include topical steroids, retinoids and vitamin D analogs in cases with limited cutaneous involvement, and systemic retinoids, methotrexate, cyclosporine and biologics (particularly infliximab). (130)