HIV Management Guide for Clinical Care

HIV Management Guide for Clinical Care

HIV-infectious Disease & Cancer

Management > HIV-infectious Disease & Cancer > Dermatological Conditions > Serious adverse drug eruptions including Stevens- Johnson syndrome and toxic epidermal necrolysis > Clinical presentation

Clinical presentation

The disease is characterised by cutaneous eruption which can take on any morphology, fever, lympadenopathy and the presence of eosinophilia or atypical lymphocytes and solid organ inflammation on laboratory investigation. Common end organs affected include the heart, lung, kidneys and liver. Mortality approaches 20% if untreated, usually as a result of hepatotoxicity. (143)

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