Serious adverse drug eruptions including Stevens- Johnson syndrome and toxic epidermal necrolysis - HIV Management Guidelines

HIV Management Guidelines

HIV Management Guidelines

HIV-infectious Disease & Cancer

Guidelines > Serious adverse drug eruptions including Stevens- Johnson syndrome and toxic epidermal necrolysis

Management > HIV-infectious Disease & Cancer > Serious adverse drug eruptions including Stevens- Johnson syndrome and toxic epidermal necrolysis

Serious adverse drug eruptions including Stevens- Johnson syndrome and toxic epidermal necrolysis

Drug reaction, eosinophilia and systemic symptoms (DRESS)

Drug reaction, eosinophilia and systemic symptoms (DRESS) is a rare severe cutaneous adverse reaction (SCAR) seen more commonly in PLWHIV. (143) DRESS can develop as a SCAR to medications, including ART agents such as abacavir or raltegrovir which demonstrate association with HLA genotypes HLA-B*57:01 and HLA-B*53:01, respectively. (144-146)

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