Identification and cessation of the causative medication is paramount. High dose corticosteroids, eg prednisolone 1mg/kg/day are the cornerstone of treatment. This is usually tapered over a period of 6-12 weeks. Guidelines do not suggest differing treatment for DRESS in PLWHIV. Following the acute phase, DRESS patients are at risk of autoimmune sequelae such as diabetes mellitus type I and thyroid disease and should be serially monitored. (148)