HIV Management Guide for Clinical Care

HIV Management Guide for Clinical Care

HIV-infectious Disease & Cancer

Management > HIV-infectious Disease & Cancer > Dermatological Conditions > Psoriasis > Clinical presentation

Clinical presentation

Plaque psoriasis is characterised by well-defined, scaley and erythematous plaques which typically affects extensor surfaces. The erythema is classically described as ‘salmon pink’ in Caucasian patients, but may appear mulberry in darker skin tones. (114) Other clinical presentations include guttate psoriasis (diffuse small papules <10mm in diameter), erythrodermic psoriasis (involving >90% of body surface area), inverse psoriasis (affecting intertriginous sites such as the axillae, submammary or inguinal creases) and pustular psoriasis (presenting with sterile, pinpoint pustules). Finger or toenail changes such as pitting, discoloration or longitudinal ridging may be present in up to 50% of patients. (115 

HIV may alter the clinical presentation and course of psoriasis, and may increase in severity with the degree of immunocompromise. (116) More extensive involvement including erythroderma with increased frequency of acral lesions and inverse psoriasis may be present in the setting of HIV. (116) 

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