HIV Treatment and Management

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INSTI interactions

Drug Interactions Between Integrase Strand Transfer Inhibitors and Other Drugs DHHS Last Updated: September 2024Australian Commentary Last Updated: December 2024 This table provides information on the known or predicted interactions between integrase strand transfer inhibitors (INSTIs) (bictegravir [BIC], dolutegravir [DTG], elvitegravir [EVG], or raltegravir [RAL]) and non-antiretroviral (ARV) drugs. EVG is always coadministered with cobicistat. […]

CCR5 Antagonist Drug Interactions

Drug Interactions Between the CCR5 Antagonist Maraviroc and Other Drugs (Including Antiretroviral Agents) DHHS Last Updated: September 2024Australian Commentary Last Updated: December 2024 Table 24e. Drug Interactions Between the CCR5 Antagonist Maraviroc and Other Drugs (Including Antiretroviral Agents) In the table below, “no dose adjustment needed” indicates that the U.S. Food and Drug Administration– approved […]

HIV-1 gp120-Directed Attachment Inhibitors

Drug Interactions Between HIV-1 gp120-Directed Attachment Inhibitors and Other Drugs (Including Antiretroviral Agents) DHHS Last Updated: September 2024Australian Commentary Last Updated: December 2024 Table 24f. Drug Interactions Between HIV-1 gp120-Directed Attachment Inhibitors and Other Drugs (Including Antiretroviral Agents) Fostemsavir (FTR), an HIV-1 gp120-directed attachment inhibitor, is a prodrug of temsavir (TMR). In this table, the […]

Capsid Inhibitor Drug Interactions

Drug Interactions Between the Capsid Inhibitor Lenacapavir and Other Drugs DHHS Last Updated: September 2024Australian Commentary Last Updated: December 2024 Table 24g. Drug Interactions Between the Capsid Inhibitor Lenacapavir and Other Drugs (Including Antiretroviral Drugs) This table provides information on the known or predicted interactions between lenacapavir (LEN), an HIV capsid inhibitor, and other drugs, […]

Interactions between PIs and NNRTIs

Interactions Between Non-Nucleoside Reverse Transcriptase Inhibitors and Protease Inhibitors DHHS Last Updated: September 2024Australian Commentary Last Updated: December 2024 Note: Interactions associated with u nboosted atazanavir (ATV), delavirdine (DLV), fosamprenavir (FPV), indinavir (IDV), lopinavir (LPV), nelfinavir (NFV), nevirapine (NVP), saquinavir (SQV), and tipranavir (TPV) are not included in this table. Please refer to the U.S. Food and Drug Administration product labels for information regarding […]

Interactions between INSTI & NNRTI or PI

Interactions between Integrase Inhibitors and Non-Nucleoside Reverse Transcriptase Inhibitors or Protease Inhibitors DHHS Last Updated: September 2024Australian Commentary Last Updated: December 2024 AU Comment: INSTI and NNRTI regimen switches NSTI metabolism via CYP3A4, concurrent use with inducers results in diminished INSTI plasma concentration – advise caution when switching from NNRTI-based to INSTI-based ART regimens due […]

Drug-Drug Interactions

This section has information on Drug-Drug Interactions. Please click on the below links or follow the table of contents to access the information you are looking for. Overview PI Drug interactions NNRTI interactions NRTI interactions INSTI interactions CCR5 Antagonist Drug Interactions HIV-1 gp120-Directed Attachment Inhibitors Interactions between PIs and NNRTIs Interactions between INSTI & NNRTI […]

Drug Name Abbreviations

DHHS Last Updated: March 2023Australian Commentary Last Updated: July 2023 AU Comment: Zidovudine The DHHS guidelines refer to Zidovudine using the acronym ‘ZDV’ however in Australian settings it referred to using the acronym ‘AZT’. The DHHS guidelines refer to Zidovudine using the acronym ‘ZDV’ however in Australian settings it referred to using the acronym ‘AZT’. […]

General Terms

DHHS Last Updated: March 2023 Acronym/Abbreviation Definition 17-BMP beclomethasone 17-monopropionate ACA Affordable Care Act ADAP AIDS Drug Assistance Program Ag/Ab antigen/antibody Al aluminum ALT alanine aminotransferase AMP average manufacturer price ART antiretroviral therapy ARTAS Anti-Retroviral Treatment and Access to Services ARV antiretroviral ASP average sales price AST aspartate aminotransferase AUC area under the curve AUD […]

Study and Trial Names

DHHS Last Updated: March 2023Australian Commentary Last Updated: July 2023 Acronym/Abbreviation Name ACTG AIDS Clinical Trials Group ADVANCE Assessing Donor Variability And New Concepts in Eligibility ARDENT ACTG A5257 trial ARTEMIS Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study ATLAS Antiretroviral Therapy as Long-Acting Suppression D:A:D Data Collection on Adverse Events of Anti-HIV Drugs ECHO […]

HIV Treatment and Management

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