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Pediatric Antiretroviral Guidelines Last updated: July 2023 The Australian ARV Guideline Committee acknowledges the updated U.S. Department of Health and Human Services HIV Guidelines (September 2025). Updates to the Australian ARV Guideline Commentary are currently on hold, pending a major update planned for late 2026. Feedback or questions can be directed to ASHM. Quick access […]
What’s New
What’s New in the Pediatric ARV Guidelines DHHS Last Updated: April 2023Australian Commentary Last Updated: July 2023 The HHS Panel on Antiretroviral Therapy and Medical Management of Children Living with HIV (the Panel) has reviewed and updated the text and references of previous versions of the Guidelines for the Use of Antiretroviral Agents in Pediatric HIV […]
Introduction
Introduction: Australian Commentary to the DHHS Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection The Australian Commentary to the DHHS Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection has been prepared by the ASHM HIV Paediatric Guidelines Committee along with external contributors (see: Contributors). The US DHHS has agreed […]
Maternal HIV Testing and Identification of Perinatal HIV Exposure
DHHS Last Updated: January 2023Australian Commentary Last Updated: July 2023 AU comment: Maternal HIV testing Expedite testing of mother as soon as practicable and if test is positive, a) intrapartum antiretroviral (ARV) prophylaxis should be initiated immediately if mother is still in labour and b) infants should receive an ARV regimen that is appropriate for infants who are at higher […]
Diagnosis of HIV in Infants and Children
DHHS Last Updated: January 2023Australian Commentary Last Updated: July 2023 AU Comment: Infant virologic diagnostic testing Australian clinicians may prefer to follow the BHIVA guidelines, which recommend virologic diagnostic testing within the first 48 hours (and prior to hospital discharge), at 2 weeks after cessation of antiretroviral prophylaxis, and at 8 weeks after cessation of antiretroviral […]
Clinical and Laboratory Monitoring of Pediatric HIV Infection
DHHS Last Updated: April 2023Australian Commentary Last Updated: July 2023 AU Comment: Monitoring children on ART Height and weight should also be monitored routinely, with drug doses adjusted according to changes in weight. Weight and BMI monitoring are particularly important in children commencing on or changing to ART regimens containing integrase inhibitors (especially bictegravir and dolutegravir) and/or tenofovir alafenamide Reference: […]
What to Start
This section has information on What to Start. Please click on the below links or follow the table of contents to access the information you are looking for. Regimens Recommended for Initial Therapy of Antiretroviral-Naive Children Regimens Not Recommended for Use in ARV-Naive Children
Regimens Recommended for Initial Therapy of ARV-Naive Children
Regimens Recommended for Initial Therapy of Antiretroviral-Naive Children DHHS Last Updated: April 2023Australian Commentary Last Updated: July 2023 AU Comment: Formulations available in Australia Limited formulations approved by the Therapeutic Goods Administration (TGA) and available via the Pharmaceutical Benefits Schedule (PBS), restrict available options for infants and children in Australia. AU Comment: Recommendations for first […]
Regimens Not Recommended for Use in ARV-Naive Children
Regimens Not Recommended for Initial Therapy of Antiretroviral-Naive Children DHHS Last Updated: April 2023 This section describes antiretroviral (ARV) drugs and drug combinations that either are not recommended for use in ARV-naive children or lack sufficient data to recommend their use in ARV-naive children. Although many ARV agents and combinations are available, some are not […]
When to Initiate Therapy in ARV-Naive Children
When to Initiate Therapy in Antiretroviral-Naive Children DHHS Last Updated: April 2023Australian Commentary Last Updated: July 2023 AU Comment: Parent/caregiver refusal to commence ART Parental of caregiver refusal to commence ART require a multidisciplinary assessment to evaluate and overcome barriers to commencing ART. Paediatric HIV health care providers should seek guidance from their respective Child […]