Introduction
Pre-Exposure Prophylaxis (PrEP) The 2025 ASHM PrEP Guidelines are now published online.Last updated: August 2025 Quick access tools Download a pdf version of the guidelines or the Decision Making In PrEP tool Guidelines PDF Decision making tool Widespread availability and uptake of human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) has the potential to significantly reduce HIV transmission […]
Key recommendations of the ASHM PrEP Guidelines Panel
The ASHM PrEP Guidelines Panel recommends that daily TD*/FTC should be recommended by clinicians as a crucial HIV-prevention strategy for all people who are at risk of HIV infection, that is, men who have sex with men (MSM), transgender people, heterosexual men and women, and people who inject drugs. The ASHM PrEP Guidelines Panel endorses […]
On-demand† PrEP is contraindicated in people with chronic hepatitis B infection
Of note, the Panel will continue to monitor the data on the efficacy of on-demand† PrEP for MSM who use on-demand† PrEP less frequently than fortnightly 14, 21.
PrEP safety and efficacy
For a full review of PrEP safety and efficacy please see the CDC “Pre-exposure prophylaxis for The prevention of hiv Infection in the united states– 2017 update” starting from page 16. https://www.cdc.gov/hiv/pdf/risk/prep/cdc-hiv-prep-guidelines-2017.pdf
References
US Preventive Services Task Force; Owens DK, Davidson KW, Krist AH, et al. Preexposure prophylaxis for the prevention of HIV infection: US Preventive Services Task Force Recommendation Statement. JAMA 2019;321:2203-13. European AIDS Clinical Society (EACS) guidelines for the treatment of HIV-positive adults in Europe. Version 9.1, October 2018. Available at: http://www.eacsociety.org/guidelines/eacs-guidelines/eacs-guidelines.html (last accessed 18 July 2019). Wright […]